Neuromodulator injections
Botulinum toxin type A
A series of tiny injections into the skin of each underarm interrupts the nerve signal that switches on the sweat glands, so the treated area produces much less sweat. It is the best evidenced treatment on the ladder for underarm sweating, and a Health Canada approved use in adults. In the pivotal randomised trial of 320 patients, 94 percent of the treated group reached at least a 50 percent reduction in sweat at 4 weeks, against 36 percent on placebo, and a 52 week study confirmed the benefit holds with repeat treatment. Treatment of the palms, soles and face is practised but off-label, more uncomfortable and less durable, and the physician explains that clearly.
Why this oneThe strongest evidence for underarm sweating, so it leads the plan.
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